The Gallaudet Family collection consists of 18 boxes of documents and nine oversized boxes filled with memorabilia and personal items belonging to the Gallaudet Family. Amongst the contents, there are correspondence, manuscripts, clippings, marriage records, and articles penned by family members, diaries, poems, and wills. The collection is divided into five series; they are Edward Miner Gallaudet Collection, Herbert Draper Gallaudet Collection, Susan Denison Gallaudet Collection, The Denison Family Collection, and the Fessenden & Gallaudet Families Collection.

These letters and documents enable researchers and subsequent generations in understanding the Gallaudet family and their intense ties with the Deaf Community.